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If gastrointestinal symptoms persist beyond the first few weeks or significantly impact your quality of life, contact your GP or diabetes specialist nurse for advice on managing symptoms or adjusting treatment

These are rare but possible

Aug 2012;60(8):1515-20

Exendin-4 is a GLP-1 analog initially located in the saliva of the Gila monster

29 CacciatoreB.PaakkariI.ToivonenJ.TikkanenM

For instance, semaglutide users face a relative risk of 2.10 for constipation compared to placebo, while tirzepatide users have an even higher relative risk of 3.36