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SKU: 84460618736

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This high selectivity enables quantification within complex biological matrices with minimal sample fractionation

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In IDH1 mutant glioblastoma, BCAT1 is transcriptionally suppressed because of the hypermethylation of three CpGs in the promoter, and this is also the consequence of IDH1 mutation-induced 2-hydroxyglutarate (2-HG) (Tonjes et al., 2013)